![johann hoffmann jarfix johann hoffmann jarfix](https://d3h6k4kfl8m9p0.cloudfront.net/stories/f.05pgwakKZ-WtSfSyqHhQ.jpg)
The disease was first described in 1891 by Guido Werdnig (1844-1919). Presents with hypotonia in infancy, with weakness in the limb, intercostal and bulbar muscles.
![johann hoffmann jarfix johann hoffmann jarfix](http://www.nms-joho.at/tn4599s30.jpg)
This reflex was documented in 1911 by his student Hans Curschmann (1875-1950). Hoffmann discussed this reflex in his teaching and used it in clinical practice, but never published. Sudden release of the flexed distal phalanx of the second, third, or fourth digits leads to flexion of the terminal phalanx of the thumb and of the last two interphalangeal joints of other fingers of that hand in the case of pyramidal tract disease affecting that limb. The ‘Hoffmann reflex’ refers to the finger reflex for hyper-reflexia associated with upper motor neuron lesions.
#JOHANN HOFFMANN JARFIX FULL#
![johann hoffmann jarfix johann hoffmann jarfix](http://www.nms-joho.at/tn4922s30.jpg)
Widely regarded as the first ‘pure’ neurologist in Germany Johann Hoffmann (1857 – 1919) was a German neurologist.